Acquisizione competenze tecnico-professionali:This 2-day will discuss the current status of botulinum neurotoxin (bont) in movement disorders and its applications in other neurological and non-neurological disorders. the workshop is divided in three main parts. the first part (day 1) will focus on pharmacological and molecular aspects of bonts. We will discuss critical issues such as the difference between brands and immunogenicity and next development of novel products and management of side effects. the second part (day 2) will focus on movement disorders and spasticity. this session is aimed to fill the gap between pathophysiology and clinical outcome of bont treatment. Experts will discuss how it is crucial to understand the mechanism of action of bont, beyond the simple muscle weakness effect.