Acquisizione competenze tecnico-professionali:In the program of this edition the faculty will provide the context for scientific exchange based on the latest research and advancements in the field, with particular attention on how to interpret and apply clinical guidelines by understanding their development, limitations, and implications for patient care. It seems important to animate discussions with the participants to understand if and how guidelines in this field influence nutrition practices, and how these interact with pharmacological interventions. the program has also been pondered to include a thorough discussion addressing the unique challenges faced by transition from the paediatric to the adult setting, and more so, on the nutritional and pharmacological approach for adults with inherited metabolic taking into account the evolution of their health in the future decades.