Acquisizione competenze tecnico-professionali:Preclinical and clinical studies demonstrate how the modulation of systemic and tumor metabolism influences crucial properties of human neoplasms, namely cancer cell growth, invasion, immunoregulation, metastasis and response to standard treatments, including chemotherapy, immunotherapy and targeted therapies. the objective of this conference is to bring together national and international experts with the aim of sharing and discussing the most recent advances in this field of research. In particular, will be discussed experimental therapeutic strategies which are able to impact on the activation status of specific populations of the immune system involved in antitumor immune response. particular attention will be paid to the clinical implications of these strategies, and in particular to metabolic treatments, both nutritional or pharmacological ones, which have demonstrated antitumor and immunomodulatory effects when used in combination with standard anticancer therapies.